HPLC Column, IEX WCX, 5um, 4.6mm ID x 100mm Length, 100A. Cogent Brand. 1 EA.

Additional Information:

Cogent IEX WCX is a weak cation exchange (WCX) HPLC stationary phase designed for the retention and separation of positively charged compounds. Manufactured using high-purity silica and carboxylic acid functional groups, the stationary phase provides a negatively charged surface within its functional pH range of approximately 2.5 to 7, enabling reliable cation exchange selectivity for basic compounds and other positively charged analytes. This chemistry is widely used in ion exchange chromatography and serves as an excellent alternative for many USP L9 methods.

67591-10P is a 100 mm x 4.6 mm ID analytical HPLC column packed with 5 µm WCX particles with a 100 Å pore size. The 100 mm column length provides an excellent balance between chromatographic resolution and analysis speed, making it well suited for routine analytical testing, pharmaceutical analysis, and method development. The 4.6 mm ID format is the industry standard for conventional HPLC systems and typically operates at approximately 1.0–2.0 mL/min, delivering robust performance and reliable method transferability.

This weak cation exchange column is particularly useful for the analysis and purification of basic pharmaceuticals, amines, peptides, proteins, and other positively charged compounds. The combination of selective WCX functionality, high-purity silica, and efficient 5 µm particles provides dependable ion exchange performance and reproducible separations for demanding analytical applications requiring improved resolution compared to shorter column formats.

Key Benefits

  • Weak cation exchange (WCX) stationary phase

  • Carboxylic acid functional groups

  • Suitable for positively charged analytes

  • Alternative for many USP L9 methods

  • High-purity silica support

  • 5 µm particles for efficient separations

  • Balanced speed and resolution with 100 mm column length

  • Reliable and reproducible ion exchange performance

Typical Applications

  • Ion exchange chromatography

  • Cation separations

  • Basic compound analysis

  • Pharmaceutical analysis

  • Amine separations

  • Peptide analysis

  • Protein analysis

  • USP L9 methods

  • Method development

  • Quality control testing

Specifications

  • Product Type: HPLC Column

  • Stationary Phase: IEX WCX

  • USP Classification: L9

  • Chromatography Mode: Weak Cation Exchange

  • Functional Group: Carboxylic Acid

  • Particle Size: 5 µm

  • Pore Size: 100 Å

  • Column Dimensions: 4.6 mm ID x 100 mm

  • Length: 100 mm

  • Recommended Flow Rate: 1.0–2.0 mL/min

  • Brand: Cogent

Important Notes

  • Designed for weak cation exchange chromatography

  • Retains positively charged analytes

  • Functional charged range approximately pH 2.5–7

  • Suitable for many USP L9 applications

  • High-purity silica provides reliable chromatographic performance

  • 100 mm column length offers an excellent balance of speed and resolution

  • Compatible with conventional HPLC systems

  • Excellent choice for routine analytical and method development applications


 

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